The analysis of the VLF signals radiated by ground transmitters and received on board of the French DEMETER satellite, reveals a drop of the signals (scattering spot) connected with the occurrence of large earthquakes.The extension of the "scattering spots" zone is large enough (1000–5000 km) and, probably, it increases with the mag
Age-related macular degeneration (AMD) is a potentially blinding posterior segment disease; inflammatory responses and subretinal drusen formation lead to leaky blood vessels.The current treatment method involves intravitreal injections of anti-VEGF agents, which is highly invasive and requires frequent injections administered by trained Steering W
When the historical data of the early phase trial and the interim data of HDMI Type A to DVI-I the Phase III trial are available, we should use them to give a more accurate prediction in both futility and efficacy analysis.The predictive power is an important measure of the practical utility of a proposed trial, and it is better than the classical
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